ENJUVIA<sup>®</sup>
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ENJUVIA® provides effective relief from the disruptive symptoms of menopause1

If you’re experiencing moderate-to-severe symptoms associated with menopause—hot flashes, night sweats, vaginal dryness, or pain with sex—you’ve come to the right place.


Here you’ll learn about natural menopause, surgical menopause, perimenopause, and how the symptoms associated with each can affect your busy life.


Discover how ENJUVIA®—a plant-based oral estrogen therapy—can provide relief by:

  • Reducing the frequency and intensity of moderate-to-severe menopausal hot flashes by 4 weeks, even at the lowest dose2,3
  • Lessening the severity of moderate-to-severe vaginal dryness and pain with sex1,4
  • Offering a range of 5 dosage strengths to better fit and adjust to your treatment needs1
    • You should discuss your ENJUVIA® dose with your healthcare professional

If you have any questions, be sure to speak with your healthcare professional. He or she can best determine if ENJUVIA® is right for you.




ENJUVIA® (synthetic conjugated estrogens, B) Tablets is a medicine that contains estrogen hormones. It is prescribed to help relieve moderate-to-severe vasomotor symptoms, including hot flashes and night sweats, and moderate-to-severe vaginal dryness and pain with sex, symptoms associated with menopause.


IMPORTANT SAFETY INFORMATION

Important health information you should know when taking estrogens like ENJUVIA®: Estrogens increase the risk for cancer of the uterus (womb). If you experience persistent or recurring vaginal bleeding while taking estrogens let your doctor know right away, as this could be a warning sign for cancer. Your doctor should check for the cause of any unusual vaginal bleeding after menopause.

Estrogens (alone or in combination with progestins) should not be used to prevent heart disease, heart attacks, strokes, or dementia.

Estrogens (alone or in combination with progestins) may increase the risk of heart attack, stroke, blood clots, and breast cancer. Estrogens (alone or in combination with progestins) may increase your risk of dementia, based on a study of women age 65 or older. Because of these risks, estrogens should be used at the lowest dose for the shortest period of time. You and your doctor should talk regularly to determine whether you still need treatment with ENJUVIA®.


Who should not use ENJUVIA®?
Do not use ENJUVIA® if you:

  • May be pregnant
  • Have had a stroke or heart attack in the past year
  • Have unusual vaginal bleeding
  • Are allergic to ENJUVIA® or any of its components
  • Have a history of certain cancers, blood clots, or liver problems

What are the common side effects with ENJUVIA®?
You may experience headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps and bloating, nausea and vomiting, or hair loss.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch,
or call 1-800-FDA-1088.

Please see the Patient Information section of the full prescribing information, including Boxed Warning.

References: 1. ENJUVIA® [package insert]. Sellersville, PA: Teva Women’s Health, Inc; 2010. 2. Utian WH, Lederman SA, Williams BM, Vega RY, Koltun WD, Leonard TW. Relief of hot flushes with new plant-derived 10-component synthetic conjugated estrogens. Obstet Gynecol. 2004;103(2):245-253. 3. Portman D, Margolis M, Reape K. Low-dose synthetic conjugated estrogens, B exhibits early onset of action in the treatment of vasomotor symptoms and vulvovaginal atrophy associated with menopause. Poster presented at: the North American Menopause Society Annual Meeting; September 30-October 3, 2009; San Diego, CA. 4. Simon JA, Reape KZ, Wininger S, Hait H. Randomized, multicenter, double-blind, placebo-controlled trial to evaluate the efficacy and safety of synthetic conjugated estrogens B for the treatment of vulvovaginal atrophy in healthy postmenopausal women. Fertil Steril. 2008;90(4):1132-1138.